Osteosarcoma

An osteosarcoma (OS) or osteogenic sarcoma (OG...

wikipedia - 13 Sep 2020
An osteosarcoma (OS) or osteogenic sarcoma (OGS) (or simply bone cancer) is a cancerous tumor in a bone. Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and that exhibits osteoblastic differentiation and produces malignant osteoid.[1]

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Inhibition of the galactosyltransferase C1GALT1 reduces osteosarcoma cell proliferation by interfering with ERK ...

Nature.com - 15 Apr 2024
Inhibition of the galactosyltransferase C1GALT1 reduces osteosarcoma cell proliferation by interfering with ERK ...  ...

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Organoselenium with electrophilic center targeting PDGFB for selective osteosarcoma radiosensitization

ScienceDirect.com - 14 Apr 2024
Organoselenium with electrophilic center targeting PDGFB for selective osteosarcoma radiosensitization  ...

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OutSmarting Osteosarcoma | Winter 2024 Synthesis | UC Davis Comprehensive Cancer Center

UC Davis Health - 24 Jan 2024
OutSmarting Osteosarcoma | Winter 2024 Synthesis | UC Davis Comprehensive Cancer Center  ...

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Advancing osteosarcoma prognosis with AI-assisted tumor cell density analysis

News-Medical.Net - 02 Apr 2024
Advancing osteosarcoma prognosis with AI-assisted tumor cell density analysis  ...

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POLE2 promotes osteosarcoma progression by enhancing the stability of CD44 | Cell Death Discovery

Nature.com - 16 Apr 2024
POLE2 promotes osteosarcoma progression by enhancing the stability of CD44 | Cell Death Discovery  ...

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Osteosarcoma survivor carves a new path forward

OHSU News - 07 Dec 2023
Osteosarcoma survivor carves a new path forward  ...

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Engineered bone marrow shows promise as cancer treatment

UC Davis Health - 18 Sep 2023
Engineered bone marrow shows promise as cancer treatment  ...

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Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma

Nature.com - 01 Apr 2024
Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma  ...

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Genetic variants associated with osteosarcoma risk: a systematic review and meta-analysis | Scientific Reports

Nature.com - 15 Feb 2024
Genetic variants associated with osteosarcoma risk: a systematic review and meta-analysis | Scientific Reports  ...

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FSP1 is a predictive biomarker of osteosarcoma cells' susceptibility to ferroptotic cell death and a potential therapeutic ...

Nature.com - 17 Feb 2024
FSP1 is a predictive biomarker of osteosarcoma cells' susceptibility to ferroptotic cell death and a potential therapeutic ...  ...

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WWOX promotes osteosarcoma development via upregulation of Myc | Cell Death & Disease

Nature.com - 05 Jan 2024
WWOX promotes osteosarcoma development via upregulation of Myc | Cell Death & Disease  ...

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Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis

Nature.com - 08 Nov 2023
Temporal chromatin accessibility changes define transcriptional states essential for osteosarcoma metastasis  ...

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Identification of an early survival prognostic gene signature for localized osteosarcoma patients | Scientific Reports

Nature.com - 27 Mar 2024
Identification of an early survival prognostic gene signature for localized osteosarcoma patients | Scientific Reports  ...

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Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational ...

Nature.com - 17 Aug 2023
Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational ...  ...

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Integrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B ...

Nature.com - 21 Feb 2024
Integrating artificial intelligence in osteosarcoma prognosis: the prognostic significance of SERPINE2 and CPT1B ...  ...

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Modeling phenotypic heterogeneity towards evolutionarily inspired osteosarcoma therapy | Scientific Reports

Nature.com - 17 Nov 2023
Modeling phenotypic heterogeneity towards evolutionarily inspired osteosarcoma therapy | Scientific Reports  ...

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RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung ...

Nature.com - 15 Feb 2024
RNA-sequencing predicts a role of androgen receptor and aldehyde dehydrogenase 1A1 in osteosarcoma lung ...  ...

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RARRES2 is involved in the “lock-and-key” interactions between osteosarcoma stem cells and tumor-associated ...

Nature.com - 27 Jan 2024
RARRES2 is involved in the “lock-and-key” interactions between osteosarcoma stem cells and tumor-associated ...  ...

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Targeting POLRMT by a first-in-class inhibitor IMT1 inhibits osteosarcoma cell growth in vitro and in vivo | Cell Death ...

Nature.com - 16 Jan 2024
Targeting POLRMT by a first-in-class inhibitor IMT1 inhibits osteosarcoma cell growth in vitro and in vivo | Cell Death ...  ...

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